WHAT IS 3F8?
3F8 is a mouse derived
monoclonal antibody developed by Dr. Cheung at Case Western Reserve University in the 1980’s, and later tested extensively at Memorial Sloan Kettering Cancer Center. It is directed toward sugar containing molecules called GD2 found on the surface of neuroblastoma cells. GD2 is also found on the surface of nerve cells. This fact is responsible for the great pain it causes while it is being infused each day. Its name, 3F8, refers to the tray, row and column it was found in when the monoclonal antibodies were screened. 3F8 has been used in clinical trials for neuroblastoma for more than 20 years. (source-http://blog.jackspack.org/what-is-3f8/)
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