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PLEASE DAVEN FOR MENACHEM SHALOM BEN MIRIAM Feel free to check in periodically for updates on our lives. We look forward to hearing from you in the comments section. Love, Miriam and Shmuel

Wednesday, October 29, 2008

"A" is for Accutane

While we are working out the details of the MSK Antibody clinical trial in NY Menschi will start taking Accutane (a standard part of treatment for neuroblastoma). He will start taking it in Atlanta. Angel Flight to Atlanta tomorrow (thurs.).
Accutane is also known as isotretinoin, 13-cis-retinoic acid, and 13-cis-RA. It is related to vitamin A and is given by mouth. Accutane has minimal toxicities when used as a therapy for children with neuroblastoma.
Accutane stops the growth of neuroblastoma. A 5 year, randomized CCG study (CCG-3891) included 539 children with high-risk neuroblastoma. The study
concluded that Accutane improved the event-free survival for children with the disease and recommended that it should be used for treating all neuroblastomas in the future.(source: ped-onc list serve)

3 comments:

Shevy said...

Who knew that a medication used for treating severe acne, that later was co-opted by women looking for younger looking skin would be effective for treating kids with neuroblastoma?

One bit of good news for you guys while you battle over the other issue.

Anonymous said...

Wow, I never knew accutane had other applications. David had very severe acne when he was 13 and was on accutane for quite awhile. It did wonders for his acne. Let's hope it's equally successful with Menschi's neuorblastoma.
Love, Uncle Michael

Anonymous said...

Hi, we just wanted to let you know that we are thinking of you always and that we miss your lovely kids so much. We would love to be in touch with them-if we would be able to get your address that would be great! please email me at batchkala@gmail.com. may we only hear good news.